Studies on the glial cell-line derived neurotrophic factor (GDNF) co-receptor α1
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چکیده
منابع مشابه
The Effects of Progesterone on Glial Cell Line-derived Neurotrophic Factor Secretion from C6 Glioma Cells
Objective(s)Progesterone is a steroid hormone whose biology has been greatly studied within the confines of reproductive function. In recent years, the neuroprotective effects of progesterone have attracted growing interest. Glial cell line-derived neurotrophic factor (GDNF), is a neurotrophic factor which plays a crucial role in the development and maintenance of distinct sets of central and p...
متن کاملCells of the human optic nerve head express glial cell line-derived neurotrophic factor (GDNF) and the GDNF receptor complex.
PURPOSE Glial cell-line derived neurotrophic factor (GDNF) is a distant member of the TGFbeta family of growth factors and has wide ranging effects within the central nervous system. In the present study we profile the expression of GDNF and its receptor complex (Ret and GFRalpha-1) in cells isolated from the human optic nerve head (ONH). METHODS Lamina cribrosa (LC) cells and ONH astrocytes ...
متن کاملکلون کردن cdnaیneurotrophic factor)gdnf(glial cell line-derived در حامل بیانی با قابلیت الحاق هدفمند در ژنوم سلول میزبان
چ فده قیقحت : هدننک دک یلاوت زا یپک ود یاراد ینایب روتکو تخاس هعلاطم نیا زا فده gdnf نایب یارب یناسنا .تسا نارادناتسپ یلولس هدر رد : قیقحت شور cds نیئتورپ gdnf صخشم یکیتامروفناویب تاعلاطم هلیسو هب یناسنا دیدرگ تفج ود کمک اب . اب هک یرمیارپ رازفا مرن oligo7.4 یحارط دندش رد هناشن دیتپپ ، n و نیئتورپ لانیمرت his-tag رد c نآ لانیمرت شور زا هدافتسا اب .تفرگ رارق t/a cloning روتکو رد هدش دی...
Effects of Glial Cell Line-derived Neurotrophic Factor (gdnf) on Mouse Fetal Ventral Mesencephalic Tissue
The symptoms of Parkinson's disease occur due to degeneration of dopamine neurons in substantia nigra. It has been demonstrated that glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor when it comes to protect and enhance survival of dopamine neurons in animal models of Parkinson's disease. The aim of this study was to evaluate shortand long-term effects of GDNF o...
متن کاملCharacterizing The Controlled Release Of Glial Cell-Line Derived (gdnf) Neurotrophic Factor From Encapsulated Schwann Cells
CHARACTERIZING THE CONTROLLED RELEASE OF GLIAL CELL-LINEDERIVED (GDNF) NEUROTROPHIC FACTOR FROM ENCAPSULATEDSCHWANN CELLS
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2002
ISSN: 0108-7673
DOI: 10.1107/s0108767302095806